WORLD REFERENCE CREATED IN MONTPELLIER IN 1989
• Specialized in ImmunoGlobulins (IG), antibodies and T cell Receptors (TR) of the adaptive immune response
• 7 databases of sequences, genes and structures
• 7 analysis tools
• 25 000 pages of Web resources
STUDIES OF IG AND TR REPERTOIRES
• Basic, clinical & veterinary research:
- Infection, cancer, autoimmune diseases, immunodeficiency syndromes
- Diagnosis, prognosis and therapeutic follow-up of patients with leukaemia, lymphoma and myeloma
- Therapeutic approaches (grafts, immunotherapy, vaccinology)
• Genomic research
• 2D-3D structural biology (IMGT Colliers de Perles, domains of the IgSF and MhSF proteins)
High throughput analysis-IMGT®/HighV-QUEST
DEVELOPMENT OF CUSTOMIZED SEQUENCE ANALYSIS TOOLS
• Engineering of single chain Fragment variable (scFv) antibodies, Fab, combinatorial libraries, phage display, ...
• Chimeric, humanized and human antibodies
FACILITY