PREPARATION OF BIOLOGICAL SAMPLES
• Biological fluids (blood, urine)
• Cell culture
• Tissue samples
Purification, separation, pre-fractionation (electrophoresis or chromatography), Digestion & enrichment
HIGH-SENSITIVITY SIMPLEX OR MULTIPLEX IMMUNOASSAYS
• Quantification of biomarkers
• Quantitative analysis of more than 350 markers (incl. cytokines, receptors, etc...). Full list here.
Single Molecule Array (SIMOA), electroluminescence detection
PROTEIN IDENTIFICATION & QUANTIFICATION
• Large scale proteomic studies by mass spectrometry
• Targeted quantification of proteins and small molecules (PRM & MRM)
• Protein-protein or protein/small molecule interactomics
• Characterization and validation of biomarkers
• Post-translational modifications (ubiquitylation, phosphorylation, ...)
LC-MSMS & SPR
ASSOCIATED BIO-INFORMATICS AND STATISTICAL ANALYSES
• Identification and quantification of proteins
• Functional analysis of biological networks of proteins
Data retreatment (quality control, bias identification, normalization, identification, quantification, validation) and design & development of data retreatment pipelines.
FACILITY